Gaëtan Ligat

Title: Gaëtan Ligat: Innovator in the Fight Against HCMV Related Diseases

Introduction

Gaëtan Ligat, an esteemed inventor based in Limoges, France, has made significant contributions to the medical field through his innovative research. Recognized for his dedication to developing treatments for HCMV (Human Cytomegalovirus) related diseases, he holds a patent that showcases his groundbreaking work in this area.

Latest Patents

Ligat's patent, titled "Antibodies and peptides to treat HCMV related diseases," focuses on identifying essential domains for the interaction between pUL56 and pUL89, proteins implicated in the disease's progression. His research utilized sequence alignments to predict a crucial interaction region within the C-terminal of pUL56. Through methods such as BAC mutagenesis and AlphaLISA technologies with purified proteins, Ligat established the significant role of the short sequence WMVVKYMGFF (SEQ ID NO: 1). This discovery led to the development of antibodies and peptides that could potentially inhibit this interaction, paving the way for new therapeutic approaches in treating HCMV related illnesses.

Career Highlights

Throughout his career, Gaëtan Ligat has been associated with notable institutions that have fortified his expertise and credibility in the medical research community. He has worked with Inserm (Institut National De La Santé Et De La Recherche Médicale) and the Centre Hospitalier Régional Universitaire De Limoges, contributing to various projects that target pressing health issues.

Collaborations

Collaboration is key in scientific advancement, and Ligat has partnered with talented colleagues, including Sophie Alain and Sébastien Hantz. Together, they have worked on various initiatives aimed at enhancing our understanding and management of viral diseases, particularly focusing on the intricate mechanisms of HCMV.

Conclusion

Gaëtan Ligat's innovative contributions, encapsulated in his patent for antibodies and peptides to treat HCMV related diseases, highlight the critical role of inventors in advancing medical science. His work not only provides hope for effective treatment options but also underscores the importance of collaboration in the scientific community. As research continues to evolve, Ligat remains a pivotal figure in the ongoing battle against viral diseases.