Company Filing History:
Years Active: 1996-2007
Title: G Terrance Walker: Innovator in Nucleic Acid Detection
Introduction
G Terrance Walker is a prominent inventor based in Chapel Hill, NC (US). He has made significant contributions to the field of molecular biology, particularly in the detection of nucleic acid sequences. With a total of 11 patents to his name, Walker's work has advanced the methodologies used in genetic research and diagnostics.
Latest Patents
One of Walker's latest patents is focused on methods for detecting single nucleotide polymorphisms. This invention provides innovative techniques for identifying sequence variations in nucleic acids using a detector primer. The method leverages the reduced efficiency of primer extension by DNA polymerases when mismatches occur at the 3' end of the primer. This allows for the discrimination between different nucleotide sequences, making it particularly useful for detecting mutations in genes. Another notable patent involves universal probes and methods for the detection of nucleic acids. This invention utilizes signal primers that employ fluorescence quenching mechanisms to detect target sequences. The conformational changes in the reporter probe, triggered by the presence of the target, enable precise identification of nucleic acid sequences.
Career Highlights
G Terrance Walker is currently associated with Becton Dickinson and Company Limited, where he continues to innovate in the field of nucleic acid detection. His work has not only contributed to scientific advancements but has also had practical applications in medical diagnostics.
Collaborations
Walker has collaborated with notable colleagues, including James G Nadeau and C Preston Linn. These partnerships have fostered a collaborative environment that enhances the research and development of new technologies in molecular biology.
Conclusion
G Terrance Walker's contributions to the field of nucleic acid detection exemplify the impact of innovative thinking in science. His patents reflect a commitment to advancing genetic research and improving diagnostic methods.