Company Filing History:
Years Active: 2016-2018
Title: Friederike Nollmann: Innovator in Modified Antibiotic Peptides
Introduction
Friederike Nollmann is a notable inventor based in Frankfurt am Main, Germany. She has made significant contributions to the field of antibiotic peptides, focusing on enhancing their stability and pharmacokinetics. With a total of 2 patents, her work is paving the way for advancements in medical treatments.
Latest Patents
Nollmann's latest patents revolve around modified antibiotic peptides, particularly derivatives of apidaecin and oncocin. These inventions aim to provide increased stability, reduced immunoreaction, and improved pharmacokinetics. The peptide antibiotics are designed to be reversibly protected by a linker made of polyethylene glycol (PEG). This innovative approach includes a recognition sequence for trypsin-like serum proteases, allowing for the selective release of the active peptide in the serum. Remarkably, the remnants of the linker that remain bonded to the amino group in the side chain do not significantly impair the antimicrobial activity of the peptide.
Career Highlights
Throughout her career, Nollmann has worked with prestigious institutions, including the University of Leipzig. Her research has contributed to the understanding and development of antibiotic therapies, showcasing her expertise in the field.
Collaborations
Nollmann has collaborated with notable colleagues such as Ralf Hoffmann and Nicole Berthold, further enhancing her research and contributions to the scientific community.
Conclusion
Friederike Nollmann's innovative work in modified antibiotic peptides demonstrates her commitment to advancing medical science. Her patents reflect a significant step forward in the development of effective antibiotic treatments.