Company Filing History:
Years Active: 1999
Title: The Innovations of Frederick Waldman
Introduction
Frederick Waldman is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of genomics, particularly through his innovative patent related to Comparative Genomic Hybridization (CGH). His work has implications for understanding genetic variations and abnormalities in various genomes.
Latest Patents
Waldman's most recent patent focuses on Comparative Genomic Hybridization (CGH). This invention discloses new methods that utilize in situ hybridization to detect abnormal nucleic acid sequence copy numbers in one or more genomes. The methods involve the removal or suppression of repetitive sequences that bind to multiple loci in a reference chromosome spread. The CGH technique allows for the determination of the relative number of copies of nucleic acid sequences in subject genomes, such as tumor cells, by comparing the intensity of signals from labeled nucleic acids to a reference genome. This innovation enables the detection of amplifications, duplications, and deletions in subject genomes, as well as the absolute copy numbers of RNA or DNA sequences in cell populations. Waldman holds 1 patent for this groundbreaking work.
Career Highlights
Frederick Waldman is affiliated with the University of California, where he has contributed to various research initiatives. His expertise in genomics and hybridization techniques has positioned him as a valuable asset in the scientific community. His work has paved the way for advancements in genetic research and diagnostics.
Collaborations
Waldman has collaborated with esteemed colleagues such as Daniel Pinkel and Joe W Gray. These partnerships have further enhanced the impact of his research and innovations in the field of genomics.
Conclusion
Frederick Waldman's contributions to the field of genomics through his patent on Comparative Genomic Hybridization exemplify the importance of innovation in understanding genetic complexities. His work continues to influence research and applications in genetic diagnostics and therapy.