Frances I Smith

Title: Frances I Smith: Innovator in Gene Delivery Systems

Introduction

Frances I Smith is a notable inventor based in Lincoln, MA (US). She has made significant contributions to the field of gene therapy through her innovative work on hybrid vector systems. Her research focuses on enhancing the delivery of genetic material into cells, which has important implications for medical treatments.

Latest Patents

Frances I Smith holds a patent for HSV/AAV hybrid amplicon vectors. This invention relates to a hybrid vector system that incorporates elements of herpesvirus and adeno-associated virus. The system is capable of expressing a gene product in eukaryotic cells. It provides a means of packaging plasmid DNA into highly infectious virions, which can efficiently and safely deliver large transgenes to both mitotic and postmitotic cells. The invention is particularly valuable for introducing and expressing gene sequences in these types of cells.

Career Highlights

Frances I Smith is associated with The General Hospital Corporation, where she continues her research and development in gene therapy. Her work has been instrumental in advancing the understanding and application of hybrid vector systems in medical science.

Collaborations

Some of her notable coworkers include Xandra O Breakefield and David R Jacoby. Their collaborative efforts contribute to the ongoing research and development in the field of gene delivery systems.

Conclusion

Frances I Smith's innovative work in hybrid vector systems represents a significant advancement in gene therapy. Her contributions are paving the way for more effective treatments in the future.