Title: Fei Xu - Innovator in G-Protein Coupled Receptors
Introduction
Fei Xu is an accomplished inventor based in Palm Beach Gardens, FL (US). He has made significant contributions to the field of biochemistry, particularly in the area of G-protein coupled receptors (GPCRs). Although he currently holds no granted patents, his work is noteworthy for its potential impact on drug discovery and development.
Latest Patent Applications
Fei Xu's latest patent applications include a detailed exploration of novel fusion partners for the purpose of crystallizing G-protein coupled receptors. The application describes GPCR-fusion partner proteins that comprise G protein coupled receptors and fusion partners such as rubredoxin, cytochrome b562 RIL, T4 lysozyme C-terminal fragment, flavodoxin, or xylanase. These proteins are either substituted for some or all of the third intracellular loop of the GPCR or attached to an terminus or C terminus of the GPCR. The application emphasizes the importance of GPCR-fusion partner proteins in crystalline form, which are suitable for x-ray crystallographic structure determination of the GPCR. Additionally, methods for using fusion partners to support crystallization and for identifying other suitable fusion partners through screening of protein data banks are also described.
Conclusion
Fei Xu's innovative work in the field of GPCRs highlights his potential as a leading inventor in biochemistry. His latest patent applications reflect a commitment to advancing scientific knowledge and improving drug development processes.