Location History:
- Cambridge, MA (US) (2014)
- Warwick, RI (US) (2015)
Company Filing History:
Years Active: 2014-2015
Title: Fei Liu: Innovator in Cell Culture Technology
Introduction
Fei Liu is a prominent inventor based in Warwick, Rhode Island, known for his contributions to the field of cell culture technology. With a total of two patents to his name, Liu has made significant advancements that enhance the understanding of cell dynamics and interactions.
Latest Patents
Liu's latest patents include a bio-matrix stretcher, which provides innovative techniques for measuring and characterizing the dynamics of cell traction forces. This invention features tunable elastic gel substrates that can be arranged in multi-well plates, allowing for a uniform predetermined thickness. The multi-well plate can be loaded with gels of varying shear moduli, and an array of punch indenters can be attached to a loading platen. These indenters apply tensile or compressive strains to the gel substrates, with the magnitude, duration, and frequency of the strain controlled by a motor assembly linked to a control system. This apparatus is designed for long-term cell culture experiments, enabling observation of cell behavior under strain. Another patent involves a multi-well culture plate that supports a range of compliant substrates, allowing for the testing of cellular responses across a plate with shear modulus from 50 to 51,200 Pascals. The plates are compatible with standard 96-well and 384-well assays, supporting the attachment and growth of various cell types.
Career Highlights
Fei Liu works at Harvard College, where he continues to push the boundaries of research in cell culture technology. His work has implications for various applications in biomedical research and tissue engineering.
Collaborations
Liu collaborates with notable colleagues, including Daniel Tschumperlin and Justin Mih, contributing to a dynamic research environment that fosters innovation.
Conclusion
Fei Liu's contributions to cell culture technology through his patents reflect his commitment to advancing scientific understanding and practical applications in the field. His work continues to inspire future innovations in cell dynamics and culture methodologies.
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