Fabienne Charles De La Brousse

Title: Fabienne Charles De La Brousse: Innovator in Gene Expression Regulation

Introduction

Fabienne Charles De La Brousse is a notable inventor based in San Francisco, CA (US). She has made significant contributions to the field of pharmacology, particularly in the regulation of gene expression. With a total of 4 patents, her work has the potential to impact various aspects of health and medicine.

Latest Patents

One of her latest patents is focused on cell-based drug screens for regulators of gene expression. This invention provides methods and compositions for screening pharmacological agents that regulate gene expression in mammals. The exemplary assay involves contacting a mammalian cell with a candidate agent and measuring the expression of a reporter to determine if the agent modulates gene expression.

Another significant patent addresses drug screens for regulators of the expression of the obese gene. This invention offers methods for screening pharmacological agents that regulate satiety, fat metabolism, and type II diabetes mellitus in mammals. The assay involves using a mammalian adipocyte with a mutant ob allele and measuring the expression of a reporter to assess the modulation of ob gene expression.

Career Highlights

Fabienne is currently employed at Tularik Limited, where she continues to advance her research in gene expression regulation. Her innovative approaches have garnered attention in the scientific community, contributing to the understanding of gene regulation and its implications for health.

Collaborations

Fabienne has collaborated with notable colleagues, including Jin-long Chen. These collaborations have further enriched her research and expanded the impact of her inventions.

Conclusion

Fabienne Charles De La Brousse is a pioneering inventor whose work in gene expression regulation holds promise for advancements in pharmacology and medicine. Her contributions are shaping the future of health-related innovations.