Title: Eva-Maria Dehne: Innovator in Microfluidic Devices
Introduction: Eva-Maria Dehne is a prominent inventor based in Berlin, Germany. She is associated with Tissuse GmbH, where she focuses on developing innovative microfluidic devices. Although she currently holds no granted patents, her contributions to the field of microphysiological systems are noteworthy.
Latest Patent Applications: Eva-Maria Dehne's latest patent application is titled "Novel Microfluidic Devices Implementing Blood and Urine Circuit for Emulating Homeostatic Microphysiological System." This application relates to novel microfluidic devices designed for operating microphysiological systems. These devices are particularly useful for pharmacokinetic-pharmacodynamic analysis in the context of ADME(T) profiling. The application describes microfluidic devices that include a first 'blood' circuit with one or more cell culture compartments and a second 'urine' circuit comprising a renal filtration and reabsorption unit. Both circuits are interconnected via the filtration and reabsorption units. The disclosure also provides methods, kits, and assays that utilize these novel microfluidic devices.
Conclusion: Eva-Maria Dehne is making significant strides in the field of microfluidics, with her innovative applications poised to impact pharmacokinetic studies and microphysiological systems.