Company Filing History:
Years Active: 2010
Title: Emilie Danve: Innovator in Pneumococcus Conjugate Development
Introduction
Emilie Danve is a notable inventor based in Tassin la Demi Lune, France. She has made significant contributions to the field of immunology through her innovative work on pneumococcus serotype 5 capsular polysaccharide conjugates. Her research focuses on improving the immunogenicity of these conjugates, which are crucial for vaccine development.
Latest Patents
Emilie Danve holds one patent titled "Conjugates obtained by reductive amination of the pneumococcus serotype 5 capsular polysaccharide." This invention relates to conjugates derived from the reductive amination of the pneumococcus serotype capsular polysaccharide. The unique conditions for reductive amination proposed by Danve help avoid the formation of an undesirable compound that negatively impacts the immunogenicity of the conjugates. In carbon NMR spectrum analysis, this undesirable compound is characterized by a resonance signal between 13 and 14 ppm. The aminated polysaccharides used in her method lack this resonance signal, ensuring better immunogenic properties. Danve's invention offers two methods for reductive amination, one involving slightly acidic pH conditions and the other involving a sequence of reduction, fragmentation, and reductive amination.
Career Highlights
Emilie Danve has established herself as a key figure in her field, working at Aventis Pasteur S.A., a company known for its contributions to vaccine development. Her innovative approaches and research have positioned her as a valuable asset in the scientific community.
Collaborations
Danve has collaborated with notable colleagues, including Noëlle Mistretta and Monique Moreau. These collaborations have further enhanced her research and contributed to the advancement of immunological studies.
Conclusion
Emilie Danve's work on pneumococcus conjugates represents a significant advancement in vaccine development. Her innovative methods and dedication to improving immunogenicity are commendable and highlight her role as a leading inventor in the field.