Elisa Guida

Title: Elisa Guida: Innovator in Cancer Research

Introduction

Elisa Guida is a prominent inventor based in Trieste, Italy. She has made significant contributions to the field of cancer research through her innovative work on peptides and aptamers. Her research focuses on targeting mutant p53 proteins, which are often associated with various cancers.

Latest Patents

Elisa Guida holds a patent titled "Peptides and aptamers thereof as specific modulators of mutant p53 function." This patent discloses isolated peptides and aptamers that can interact with structural and conformational p53 mutants. These interactions occur within the wild-type p53 DNA binding core domain, specifically from amino acids 74 to 298. The yeast two-hybrid method was utilized to identify these peptides and aptamers, which can efficiently recognize several different p53 point mutants while not affecting the wild-type p53. The identified peptides and aptamers have potential applications as inhibitors of mutant p53-associated pro-oncogenic functions, making them valuable for anticancer therapy and diagnostic tools.

Career Highlights

Elisa Guida is affiliated with the Università Degli Studi Di Trieste, where she continues her research and development in the field of molecular biology and cancer therapeutics. Her work has garnered attention for its potential to lead to new treatments and diagnostic methods for cancers associated with mutant p53.

Collaborations

Elisa collaborates with notable colleagues such as Giannino Del Sal and Andrea Bisso. Their combined expertise enhances the research efforts in understanding and targeting mutant p53 functions.

Conclusion

Elisa Guida's innovative work in cancer research, particularly her patent on peptides and aptamers targeting mutant p53, showcases her commitment to advancing therapeutic options for cancer treatment. Her contributions are paving the way for future developments in the field.