Company Filing History:
1 out of 832,891 Years Active: 2001
Title: Elin Lunde - Innovator in Immunology
Introduction
Elin Lunde is a prominent inventor based in Oslo, Norway. She has made significant contributions to the field of immunology, particularly through her innovative work on modified immunoglobulin molecules. Her research focuses on enhancing the immune response, which has important implications for cancer treatment and vaccination strategies.
Latest Patents
Elin Lunde holds a patent for a "Modified immunoglobulin molecule incorporating an antigen in a non-CDR loop region." This invention involves a modified immunoglobulin (Ig) molecule that incorporates foreign antigenic peptides, such as a ras peptide, in one or more non-CDR loops. The antigen binding site of the immunoglobulin is designed to recognize dendritic antigen presenting cells (APCs). This allows the modified Ig to be taken up by dendritic APCs, presenting the foreign antigenic peptide on MHC II to naive T-helper cells. This process stimulates cytotoxic T-cells through the production of interleukin-2 (IL-2). The modified Igs can be utilized to stimulate the immune system, particularly in cases where tolerance has developed towards a mutant protein, such as in certain cancers, or for vaccination against viral infections. The modified Ig can be expressed from recombinant host cells, ensuring its secretion despite the presence of the foreign peptide in a loop of the molecule.
Career Highlights
Elin Lunde has established herself as a key figure in immunological research. Her innovative approaches have garnered attention in the scientific community, leading to advancements in therapeutic strategies for various diseases.
Collaborations
Elin has collaborated with notable colleagues, including Bjarne Bogen and Inger Sandlie. These partnerships have further enriched her research and contributed to the development of her patented technologies.
Conclusion
Elin Lunde's work in the field of immunology exemplifies the impact of innovative thinking on medical science. Her patented inventions hold promise for enhancing immune responses and improving treatment options for patients.