Philadelphia, PA, United States of America

Edward S Schulman


Average Co-Inventor Count = 1.5

ph-index = 1

Forward Citations = 8(Granted Patents)


Company Filing History:


Years Active: 2002-2009

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3 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Edward S. Schulman

Introduction

Edward S. Schulman is a notable inventor based in Philadelphia, PA, who has made significant contributions to the field of biomedical research. With a total of 3 patents to his name, Schulman's work primarily focuses on human lung mast cells and their implications in various diseases.

Latest Patents

Schulman's latest patents include groundbreaking methods for culturing human lung mast cells. One of his patents describes methods for culturing these cells in the absence of co-culture with feeder cells, allowing for longer viability beyond four days. This innovation enables researchers to assess the biological and pharmacological activities of human lung mast cells in vivo. Furthermore, it aids in identifying modulators that can influence the survival, proliferation, function, and phenotypic expression of these cells, which are crucial for preventing and treating diseases related to lung mast cell function.

Another significant patent focuses on the modulation of human mast cell activation through ATP binding to P2-purinoceptors on the mast cell surface. This discovery provides a potential target for therapeutic intervention in disorders characterized by undesirable mast cell mediator release, such as asthma and allergies. The patent outlines inhibitors of ATP binding to mast cell P2-purinoceptors as useful therapeutic agents for treating these conditions.

Career Highlights

Throughout his career, Schulman has worked with various organizations, including Duska Scientific Company and the Philadelphia Health and Education Corporation. His experience in these companies has contributed to his expertise in the field of biomedical research and innovation.

Collaborations

Schulman has collaborated with notable professionals in his field, including Amir Pelleg, enhancing the impact of his research and inventions.

Conclusion

Edward S. Schulman's innovative work in the field of human lung mast cells has the potential to significantly advance therapeutic approaches for respiratory diseases. His contributions continue to influence research and development in biomedical science.

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