Company Filing History:
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1 out of 7 Years Active: 2019
Title: Duy Tran Mai: Innovator in Rhinovirus Research
Introduction
Duy Tran Mai is a notable inventor based in Seattle, WA, recognized for his contributions to the field of virology. His innovative work focuses on the prevention and treatment of rhinovirus infections, which are a significant cause of respiratory illnesses.
Latest Patents
Duy Tran Mai holds a patent titled "Compositions and methods for preventing and treating rhinovirus infections." This patent involves an analysis of human CD4T-cell epitopes of rhinovirus capsid proteins with cross-reactive potential. The research identified peptide epitopes of RV-A16 capsid proteins VP1 and VP2. It was found that circulating RV-A16-specific CD4T cells targeted ten unique epitopes with diverse HLA-DR binding capacity among non-infected subjects. The study highlighted that T-cell epitopes localized to conserved regions of significance to the virus and were enriched for HLA class I and II binding motifs. These epitopes were activated in vivo after experimental infection with RV-A16. The findings indicated that RV-A16 epitopes provided approximately 90% coverage of the US population, with evidence of cross-reactivity for RV-A16 and RV-A39. High-frequency circulating RV-specific memory Th1 cells in healthy individuals preferentially targeted a limited set of conserved epitopes, which can serve as potential vaccine candidates.
Career Highlights
Throughout his career, Duy Tran Mai has worked with prestigious institutions, including the University of Virginia and the Benaroya Research Institute at Virginia Mason. His research has significantly advanced the understanding of rhinovirus infections and their immune responses.
Collaborations
Duy Tran Mai has collaborated with esteemed colleagues, including Judith Ann Woodfolk and Lyndsey M Muehling, contributing to the collective knowledge in the field of virology.
Conclusion
Duy Tran Mai's innovative research and patent in rhinovirus infections exemplify his commitment to advancing medical science. His work not only enhances our understanding of viral infections but also paves the way for potential therapeutic interventions.