Company Filing History:
Years Active: 2020-2023
Title: Duncan Freake: Innovator in Microphysiological Systems
Introduction
Duncan Freake is a notable inventor based in Boston, MA (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of advanced microphysiological systems. With a total of 2 patents, his work focuses on enhancing the understanding of multi-organ interactions.
Latest Patents
Freake's latest patents include a modular organ microphysiological system with integrated pumping, leveling, and sensing. This innovative platform utilizes fluidic multiwell bioreactors for in vitro investigation of multi-organ crosstalk over extended periods, ranging from weeks to months. The system features several improvements over existing bioreactors, such as on-board pumping for pneumatically driven fluid flow, a redesigned spillway for self-leveling, and a non-contact built-in fluid level sensing device. Additionally, it allows for precise control of fluid flow profiles and partitioning, along with easy reconfigurations like daisy chaining and multilayer stacking. This platform supports the culture of multiple organs in an interactive microphysiological system, making it suitable for various biomedical applications, including systemic toxicity studies and physiology-based pharmacokinetic and pharmacodynamic predictions.
Career Highlights
Duncan Freake is affiliated with the Massachusetts Institute of Technology, where he continues to push the boundaries of research in microphysiological systems. His work has garnered attention for its potential to revolutionize the way biomedical research is conducted.
Collaborations
Freake collaborates with esteemed colleagues, including Linda G Griffith and David L Trumper, who contribute to the advancement of his research initiatives.
Conclusion
Duncan Freake's innovative contributions to microphysiological systems exemplify the intersection of engineering and biomedical research. His patents reflect a commitment to improving in vitro investigation methods, paving the way for future advancements in the field.