Dongli Pan

Title: Innovations of Dongli Pan in Protein Synthesis

Introduction

Dongli Pan is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of molecular biology, particularly in the area of protein synthesis. With a total of 4 patents, his work has advanced our understanding of transfer RNA and its applications.

Latest Patents

One of Dongli Pan's latest patents focuses on the fluorescent labeling of transfer RNA and the study of protein synthesis. This invention provides methods for labeling transfer RNA by replacing the uracil component of a dihydrouridine with a fluorophore. The methods can be applied to both natural tRNAs, synthesized in various cell types, and synthetic tRNAs. Additionally, the invention outlines methods for assessing protein synthesis in a translation system. This involves introducing a labeled tRNA into the system, irradiating it with electromagnetic radiation to generate a fluorescence signal, and detecting this signal to correlate it with characteristics of protein synthesis. These methods are valuable in both single molecule and ensemble settings.

Career Highlights

Dongli Pan has worked with prestigious institutions, including the University of Pennsylvania and Anima Cell Metrology. His experience in these organizations has contributed to his expertise in the field of molecular biology and patent development.

Collaborations

Throughout his career, Dongli Pan has collaborated with notable individuals such as Barry S Cooperman and Zeev Smilansky. These collaborations have likely enriched his research and innovation efforts.

Conclusion

Dongli Pan's contributions to the field of protein synthesis through his innovative patents demonstrate his significant role as an inventor. His work continues to influence research and applications in molecular biology.