Company Filing History:
Years Active: 2013
Title: Innovations of Dong-Uk Hwang in Epileptogenesis Detection
Introduction
Dong-Uk Hwang is a notable inventor based in Daejeon, South Korea. He has made significant contributions to the field of neuroscience, particularly in understanding epileptogenesis. His innovative work focuses on the detection of neuronal excitation and inhibition in the brain, which is crucial for developing therapeutic measures for epilepsy.
Latest Patents
Dong-Uk Hwang holds a patent for a method and system for detecting epileptogenesis. This patent describes a process where neuronal activity is tracked in the hippocampal CA1 network during a latent period. The method identifies biomarkers, including a sustained increase in the firing rate of excitatory postsynaptic field activity, alongside a decrease in inhibitory postsynaptic field activity. The findings reveal that both excitatory and inhibitory CA1 field activity firing rates follow a circadian rhythm that changes during epileptogenesis. Additionally, a change in the circadian rhythm of core body temperature is noted as a significant biomarker. Therapeutic measures suggested in the patent include thermal, chemical, or electrical modulation.
Career Highlights
Dong-Uk Hwang is affiliated with the University of Florida Research Foundation, Incorporated. His work has been instrumental in advancing the understanding of epilepsy and its underlying mechanisms. His research has the potential to lead to innovative therapeutic approaches for individuals suffering from this condition.
Collaborations
Dong-Uk Hwang has collaborated with notable researchers such as Sachin S Talathi and William Lawrence Ditto. These collaborations have contributed to the depth and breadth of his research in the field of neuroscience.
Conclusion
Dong-Uk Hwang's innovative work in detecting epileptogenesis represents a significant advancement in neuroscience. His contributions have the potential to improve therapeutic strategies for epilepsy, showcasing the importance of research in understanding complex neurological conditions.