Company Filing History:
3 out of 470 
1 out of 30 
1 out of 4 Years Active: 2002-2022
Title: Diane Lipscombe: Innovator in Neuroscience
Introduction
Diane Lipscombe is a prominent inventor based in Barrington, RI (US). She has made significant contributions to the field of neuroscience, particularly in the area of excitable cells and their control mechanisms. With a total of 4 patents, her work has the potential to impact various neurological conditions.
Latest Patents
One of her latest patents is titled "Minimally-invasive and activity-dependent control of excitable cells." This invention provides a method of bioluminescence-driven optogenetic control of excitable cells. The excitable cell expresses a light-gated ion channel, and a luminescent protein can be expressed either in the excitable cell or in another cell proximal to the excitable cell. The methods of this invention can be used to desynchronize local activity of excitable cells in mammalian tissue. Furthermore, these methods can be utilized to treat diseases or conditions in mammals, such as Parkinson's disease, epilepsy, sleep disorders, or sensory-related diseases like attention deficit disorder or pain.
Another significant patent is "Human N-type calcium channel isoform and uses thereof." This invention pertains to a human N-type calcium channel isoform, hα, which is involved in central nervous system signaling. It includes fragments and biologically functional variants of the human hα channel. Additionally, the invention covers human N-type calcium channel hα subunit inhibitors that inhibit the expression or function of this subunit. The invention further relates to methods of using such nucleic acids, polypeptides, and inhibitors in the treatment and/or diagnosis of diseases, including methods for treating stroke, neuropathic pain, and traumatic brain injury.
Career Highlights
Diane Lipscombe has had a distinguished career, working at notable institutions such as Brown University and Central Michigan University. Her research has focused on understanding the mechanisms of excitable cells and their implications for neurological health.
Collaborations
Throughout her career, Diane has collaborated with esteemed colleagues, including Stephanie Schorge and Christopher I. Moore. These collaborations have enriched her research and contributed to her innovative work in neuroscience.
Conclusion
Diane Lipscombe's contributions to the field of neuroscience through her patents and research have the potential to advance our understanding and treatment of various neurological conditions. Her innovative approaches continue to inspire future research in this critical area