Company Filing History:
3 out of 44 
1 out of 389 
Years Active: 1997-2001
Title: Dennis W Metzger: Innovator in Immunology
Introduction
Dennis W Metzger is a notable inventor based in Sylvania, Ohio, who has made significant contributions to the field of immunology. He holds three patents that focus on enhancing immune responses, particularly in relation to T-independent antigens and neonatal immunity. His work has implications for improving health outcomes in various populations.
Latest Patents
One of Metzger's latest patents is titled "IL-12 enhancement of immune responses to T-independent antigens." This invention describes a method for modulating immune responses in hosts, including humans, by administering interleukin-12 (IL-12) alongside T-cell independent antigens. The patent outlines various embodiments aimed at inducing and enhancing humoral immune responses, specifically targeting IgG2a and IgG3 responses.
Another significant patent is "IL-12 Stimulation of Neonatal Immunity." This invention focuses on inducing a Th1-like immune response against pathogens in neonatal hosts. It details methods for overcoming suppression of interferon-gamma expression in neonates exposed to pathogens, emphasizing the administration of IL-12 and relevant antigens to enhance cytokine expression.
Career Highlights
Throughout his career, Metzger has worked with esteemed institutions such as the Medical College of Ohio and Genetics Institute, Inc. His research has contributed to advancements in immunological therapies and has been pivotal in understanding immune responses in different age groups.
Collaborations
Metzger has collaborated with notable colleagues, including Victor H Van Cleave and Bernard P Arulanandam. These partnerships have fostered a collaborative environment that enhances research outcomes and innovation in the field of immunology.
Conclusion
Dennis W Metzger's contributions to immunology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the understanding and treatment of immune responses, particularly in vulnerable populations such as neonates.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.