Dennis Buda

Title: Dennis Buda: Innovator in Microbiological Assays

Introduction

Dennis Buda, based in Baltimore, MD, is a distinguished inventor recognized for his contributions to the field of microbiological assays. With a compelling innovation in the measurement of aminoglycoside antibiotics, he has made strides that resonate within the healthcare community.

Latest Patents

Buda holds a significant patent titled "Microbiological assay of aminoglycoside antibiotics." This innovative method focuses on determining the levels of aminoglycoside antibiotics, such as gentamicin, tobramycin, or amikacin, in blood serum or plasma. The process involves incubating an aliquot of blood serum or plasma from a human patient being treated with an aminoglycoside antibiotic in a urea-containing culture medium. This medium is combined with a susceptible strain of an adaptive urease-producing microorganism, specifically Proteus rettgeri JLI 03, ATCC No. 31168, thus enabling accurate measurement of antibiotic levels in clinical settings.

Career Highlights

Dennis Buda is currently employed at Johnston Laboratories, Inc., where he applies his expertise in the development of microbiological assays. His innovative work significantly contributes to improving patient care by ensuring more accurate monitoring of antibiotic treatment efficacy.

Collaborations

Throughout his career, Buda has collaborated with notable colleagues, including Rodney L. Broman and John R. Waters. Their collective efforts have played an integral role in advancing the research and development of assays that enhance the understanding and utilization of aminoglycoside antibiotics.

Conclusion

Dennis Buda’s innovative approach to microbiological assays not only reflects his expertise but also highlights the importance of accurate antibiotic monitoring in healthcare. His patent and contributions to Johnston Laboratories, Inc. demonstrate the vital role inventors play in advancing medical science and improving patient outcomes.