Denis G Kay

Title: Denis G Kay: Innovator in Transgenic Research

Introduction

Denis G Kay is a notable inventor based in Ile Perrot, Canada. He has made significant contributions to the field of biomedical research, particularly in the development of animal models for studying diseases.

Latest Patents

Denis G Kay holds a patent for "Transgenic mice expressing HIV-1 in immune cells." This invention relates to a transgenic mouse designed to serve as a small animal model of AIDS. The mouse comprises at least a DNA sequence coding for HIV-1 nef or an HIV-1 DNA genome that essentially consists of the entire HIV-1 coding sequences. These sequences are under the control of the human CD4 gene promoter, flanked by the enhancer of the mouse CD4 gene for expression in T cells and in cells of monocyte/microphage lineage. The patent also provides a method to screen for therapeutic agents for the treatment of AIDS, which includes administering the therapeutic agent to the mouse and determining the effects of the therapeutic agent.

Career Highlights

Denis G Kay is affiliated with the Institut de Recherches Cliniques de Montreal, where he has been involved in groundbreaking research. His work has contributed to a better understanding of HIV and potential treatments for AIDS.

Collaborations

Some of his notable coworkers include Paul Jolicoeur and Zaher Hanna, who have collaborated with him on various research projects.

Conclusion

Denis G Kay's innovative work in developing transgenic models has the potential to advance the understanding and treatment of AIDS. His contributions to biomedical research are invaluable and continue to impact the scientific community.