Company Filing History:
Years Active: 1996
Title: Demetrios Vassilatis: Innovator in Genetic Engineering
Introduction
Demetrios Vassilatis is a notable inventor based in Edison, NJ (US). He has made significant contributions to the field of genetic engineering, particularly in the development of DNA encoding glutamate-gated chloride channels. His work has implications for both insecticides and anthelminthic agents.
Latest Patents
Vassilatis holds a patent for "DNA encoding glutamate gated chloride channels." This patent describes the cloning and characterization of DNAs encoding glutamate and avermectin-sensitive chloride channels. The individual alpha and beta subunits are capable of forming homomeric and heteromeric channels that can be selectively opened with either avermectin or glutamate. The cDNAs have been expressed in recombinant host cells, which produce active recombinant protein. Furthermore, the recombinant protein is purified from these host cells. This innovative approach also establishes a method for identifying modulators of receptor activity, which are useful in various applications.
Career Highlights
Demetrios Vassilatis is currently employed at Merck & Co., Inc., where he continues to advance his research in genetic engineering. His work has led to the development of important biotechnological applications that benefit both agriculture and medicine.
Collaborations
Vassilatis has collaborated with notable colleagues, including Doris F. Cully and Joseph P. Arena. These partnerships have enhanced the scope and impact of his research.
Conclusion
Demetrios Vassilatis is a pioneering inventor whose work in genetic engineering has led to significant advancements in the field. His contributions, particularly in the area of glutamate-gated chloride channels, demonstrate the potential for innovative solutions in both agricultural and medical applications.