Company Filing History:
Years Active: 2014-2016
Title: Debra Mackenzie: Innovator in Cancer Treatment
Introduction
Debra Mackenzie is a prominent inventor based in Albuquerque, NM (US). She has made significant contributions to the field of cancer treatment, holding 2 patents that focus on innovative methods for combating cancer, particularly hormone refractory prostate cancer.
Latest Patents
Mackenzie's latest patents involve methods and related compositions for the treatment and prevention of cancer. These methods comprise administering agents that cause increased intracellular granularity in cancer cells. The treatment aims to inhibit the proliferation of cancer cells and ideally lead to their death. The agents identified not only increase intracellular granularity but also convert adherent cancer cells to non-adherent ones, facilitating cancer cell death. The invention demonstrates that cancer cells can undergo increased granularity at relatively low agent concentrations while also inhibiting cell proliferation. Higher concentrations can lead to the conversion of adherent cancer cells to non-adherent cells, ultimately resulting in cell death. Although the exact mechanism of cancer cell degradation is not fully understood, treated cancer cells, including those from refractory prostate cancer, show signs of cell death through an autophagic mechanism. Additionally, pharmaceutical compositions related to these methods are also disclosed.
Career Highlights
Debra Mackenzie is associated with Stc.unm, where she continues her research and development in cancer treatment methodologies. Her work is pivotal in advancing therapeutic options for patients suffering from difficult-to-treat cancers.
Collaborations
Some of her notable coworkers include Todd A Thompson and Tudor Oprea, who contribute to her research efforts and innovations in the field.
Conclusion
Debra Mackenzie is a trailblazer in cancer treatment innovation, with her patents reflecting a commitment to improving patient outcomes through scientific advancements. Her work continues to inspire and pave the way for future research in oncology.