Location History:
- Overland Park, KS (US) (1992)
- Buffalo Grove, IL (US) (1994)
Company Filing History:
Years Active: 1992-1994
Title: Innovations in Radiolabeling: The Contributions of Deborah Kaminsky
Introduction
Deborah Kaminsky is a notable inventor based in Overland Park, Kansas, recognized for her significant contributions to the field of radiolabeling. With a total of two patents to her name, her work has advanced the methods used in scintigraphic imaging, particularly in the labeling of leucocytes.
Latest Patents
Kaminsky's latest patents include a method of labeling leucocytes with Tc-99m, d,1-HMPAO and a method for labeling leucocytes with indium In-111 oxine. The first patent describes an improved technique for radio-labeling leucocytes in vitro with Technetium-99m-d,1-hexamethyl propyleneamine oxime. This method enhances labeling efficiency by incubating leucocytes with Tc-99m d,1-HMPAO in the presence of an acid citrate dextrose solution and depleting residual red blood cells (RBCs) prior to the incubation step. The depletion of RBCs is achieved through a rocking step. The second patent focuses on an improved method for radio-labeling leucocytes in vitro with Indium In-111 oxyquinoline. This method also enhances leucocyte-specific labeling efficiency by depleting residual RBCs from the leucocytes before labeling, utilizing a similar rocking step for RBC depletion.
Career Highlights
Deborah Kaminsky has made significant strides in her career, particularly through her work at Syncor International Corporation. Her innovative approaches to radiolabeling have not only contributed to the scientific community but have also improved clinical practices in imaging inflammatory lesions and abscesses.
Collaborations
Kaminsky has collaborated with Dennis Hoogland, further enhancing the research and development of her patented methods. Their partnership has been instrumental in advancing the techniques used in scintigraphic imaging.
Conclusion
Deborah Kaminsky's contributions to the field of radiolabeling have paved the way for improved imaging techniques in medical diagnostics. Her innovative patents reflect her dedication to enhancing the efficiency and effectiveness of radiolabeling methods.