Company Filing History:
Years Active: 1997-2023
Title: David W. Russell: Innovator in Genetic Engineering
Introduction
David W. Russell is a prominent inventor based in Seattle, WA (US). He has made significant contributions to the field of genetic engineering, holding a total of 8 patents. His work focuses on innovative methods for gene modification and cellular engineering, which have important implications for medical research and treatment.
Latest Patents
Among his latest patents is the invention of Beta-2 microglobulin-deficient cells. This invention provides isolated primate cells, preferably human cells, that comprise a genetically engineered disruption in a beta-2 microglobulin (B2M) gene. This disruption results in a deficiency in MHC class I expression and function. The invention also includes methods for using these cells for transplantation and treating various disease conditions. Another notable patent is for targeted gene modification by parvoviral vectors. This invention outlines methods for achieving targeted gene modification in vertebrate cells using parvoviral vectors, including adeno-associated virus (AAV). The parvoviral vectors are capable of targeting specific genetic modifications to a preselected target locus in a cellular genome through homologous pairing.
Career Highlights
David W. Russell has worked with esteemed institutions such as the University of Washington and Fred Hutchinson Cancer Center. His career has been marked by a commitment to advancing the field of genetic research and developing innovative solutions for complex medical challenges.
Collaborations
Throughout his career, David has collaborated with notable colleagues, including Roli K. Hirata and Ian E. Alexander. These collaborations have further enriched his research and contributed to the success of his inventions.
Conclusion
David W. Russell stands out as a leading inventor in the realm of genetic engineering. His innovative patents and collaborations reflect his dedication to advancing medical science and improving treatment options for various diseases.