Company Filing History:
Years Active: 1998-2000
Title: David R. Shaffer: Innovator in Hepatitis A Vaccine Development
Introduction
David R. Shaffer is a notable inventor based in Chapel Hill, NC (US). He has made significant contributions to the field of virology, particularly in the development of vaccines for hepatitis A. With a total of 2 patents, his work has implications for public health and disease prevention.
Latest Patents
Shaffer's latest patents focus on live hepatitis A virus deletion mutants and vaccine formulations. These patents disclose live hepatitis A virus deletion mutants that possess a deletion mutation in the 5' nontranslated region of the viral genome. The deletion mutations may include pY1 deletion mutations that allow the virus to replicate in monkey kidney cells, as well as mutations between nucleotides 140 and 144 that render the virus temperature sensitive. Importantly, these deletion mutations may serve as attenuating mutations. The pharmaceutical formulations containing such viruses are designed to produce antibodies that are useful for diagnostic purposes and for providing protective immunity against hepatitis A virus.
Career Highlights
David R. Shaffer is affiliated with the University of North Carolina at Chapel Hill, where he conducts his research and development work. His academic background and professional experience have positioned him as a key figure in the field of vaccine research.
Collaborations
Due to space constraints, the details of his collaborations will not be included.
Conclusion
David R. Shaffer's innovative work in the development of hepatitis A vaccines highlights his significant contributions to medical science. His patents reflect a commitment to advancing public health through effective vaccine formulations.