Location History:
- Mira Mesa, CA (US) (1987)
- San Diego, CA (US) (1986 - 1992)
- El Cahon, CA (US) (1998)
Company Filing History:
5 out of 122 
2 out of 1,187 
1 out of 402 
Years Active: 1986-1998
Title: David R. Milich: Innovator in Hepatitis B Research
Introduction
David R. Milich is a prominent inventor based in San Diego, California. He has made significant contributions to the field of hepatitis B research, holding a total of seven patents. His work focuses on innovative methods for diagnosing and understanding chronic hepatitis B virus infections.
Latest Patents
Among his latest patents is a method for diagnosing chronic hepatitis B virus infection. This patent highlights that human antibodies binding to woodchuck hepatitis virus core antigen are elevated in chronic hepatitis B patients compared to those with acute hepatitis B. Additionally, he has developed immunoassays for detecting the level of anti-WHV core antigen antibodies, which are crucial for distinguishing between chronic and acute hepatitis B patients. Another notable patent involves T cell epitopes of the hepatitis B virus nucleocapsid protein. This patent discloses polypeptides corresponding to T cell stimulating regions of the HBV nucleocapsid protein. Furthermore, it presents a method for enhancing the immunogenicity of a polypeptide immunogen by operatively linking the polypeptide through an amino acid residue side chain to core protein particles.
Career Highlights
David R. Milich has had a distinguished career, working with esteemed organizations such as the Scripps Clinic and Research Foundation and The Scripps Research Institute. His research has significantly advanced the understanding of hepatitis B and its implications for public health.
Collaborations
Throughout his career, Milich has collaborated with notable colleagues, including Frank V. Chisari and George B. Thornton. These collaborations have further enriched his research and contributed to the advancement of hepatitis B studies.
Conclusion
David R. Milich's innovative work in hepatitis B research has led to important advancements in diagnosis and treatment. His contributions continue to impact the field and improve patient outcomes.