Location History:
- Downington, PA (US) (1995)
- Dowington, PA (US) (1996)
Company Filing History:
2 out of 247 
2 out of 730 
Years Active: 1995-1996
Title: The Innovations of David P. Rotella
Introduction
David P. Rotella is a notable inventor based in Downington, PA, who has made significant contributions to the field of neurobiology. With a total of two patents to his name, he has focused on developing compounds that enhance neurotrophin-induced activity, which is crucial for the survival and function of neurons.
Latest Patents
Rotella's latest patents include innovative derivatives of the indolocarbazole alkaloid K-252a. These derivatives are designed to enhance the neurotrophin-induced activity of neurotrophin-responsive cells, particularly those responsive to NT-3. The enhanced activity can be measured through various assays, including ChAT activity, DRG neuronal survival, and cell division. Additionally, functional K-252a derivatives are utilized to potentiate trk phosphorylation and improve the efficacy of NT-3 in treating neurological disorders.
Career Highlights
Throughout his career, David P. Rotella has worked with prominent companies such as Cephalon, Inc. and Kyowa Hakko Kogyo Co., Ltd. His work has been instrumental in advancing the understanding of neurotrophins and their role in neurological health.
Collaborations
Some of his notable coworkers include Marcie A. Glicksman and Nicola T. Neff, who have collaborated with him on various projects related to his patents and research.
Conclusion
David P. Rotella's contributions to neurobiology through his innovative patents highlight his commitment to advancing medical science. His work continues to pave the way for new treatments for neurological disorders.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.