Location History:
- Middleton, WI (US) (1996)
- Madison, WI (US) (1998 - 2004)
Company Filing History:
Years Active: 1996-2004
Title: **Innovations of David L. Northey: Pioneering Advances in Oocyte Activation**
Introduction
David L. Northey is an accomplished inventor based in Madison, WI, with a significant focus on biotechnological innovations. With a total of five patents to his name, he has contributed notably to the field of reproductive biology, particularly concerning the activation of mammalian oocytes.
Latest Patents
David Northey's latest innovations include two key patents focused on the parthenogenic activation of mammalian oocytes. The first patent outlines a process that involves increasing intracellular levels of divalent cations and reducing the phosphorylation of cellular proteins within the oocyte. This method utilizes a calcium-free cation, such as ionomycin, to enhance these conditions, and employs a serine-threonine kinase inhibitor like 6-dimethylaminopurine (DMAP) to prevent the phosphorylation of proteins within the oocyte. The second patent mirrors this innovation, emphasizing the same techniques to achieve effective parthenogenic oocyte activation.
Career Highlights
Throughout his career, David has made significant contributions while working at notable companies, including Infigen, Inc. His work in the field has had substantial implications for reproductive technologies and has opened new avenues of research and application in biotechnology.
Collaborations
David's journey in innovation has seen him collaborate with esteemed colleagues, including Joan L. Susko-Parrish and M. Lorraine Leibfried-Rutledge. Their collaborative efforts have fostered advancements in reproductive biology, expanding the understanding and capabilities in oocyte activation procedures.
Conclusion
David L. Northey's innovative approaches to mammalian oocyte activation represent a vital advancement in the field of reproductive biology. His patents not only underscore his inventive prowess but also contribute to the broader scientific community’s understanding of oocyte biology and its applications in biotechnological advancements.