Company Filing History:
Years Active: 2001
Title: The Innovations of David John Smith
Introduction
David John Smith is a notable inventor based in Turku, Finland. He is recognized for his contributions to biotechnology, particularly in the field of antibiotic production. His work has led to advancements in the synthesis of important compounds used in medicine.
Latest Patents
David John Smith holds a patent for "DNA encoding ACV synthetase." This patent describes the DNA encoding the gene for the synthetase enzyme capable of generating δ (L-a-aminoadipyl)-L-cysteinyl-D-valine (ACV) from its constituent amino acids. The DNA was obtained from several penicillin and cephalosporin-producing organisms, such as Cephalosporium and a Flavobacterium species. The patent outlines the preparation of recombinant vectors comprising the ACV synthetase gene and hosts transformed with such vectors. The ACV synthetase gene can form part of a gene cluster that includes other genes involved in β-lactam biosynthesis and the production of penicillin. This innovation allows for the expression of the entire biosynthetic gene cluster for the synthesis of penicillin from primary amino acids in suitable hosts, including heterologous hosts that are naturally non-producers of penicillin.
Career Highlights
Throughout his career, David John Smith has worked with prominent companies in the biotechnology sector. He has been associated with Beecham Group Plc and Biotie Therapies Corporation, where he contributed to various research and development projects. His expertise in genetic engineering and biochemistry has made a significant impact on the field.
Collaborations
David has collaborated with several professionals in his field, including Martin Karl Russell Burnham and Alison Jane Earl. These collaborations have fostered innovation and have led to advancements in the development of new biotechnological solutions.
Conclusion
David John Smith's contributions to biotechnology, particularly through his patent on ACV synthetase, highlight his role as an influential inventor. His work continues to inspire advancements in antibiotic production and genetic engineering.