New Haven, CT, United States of America

David J Leffell

Average Co-Inventor Count = 22.0

ph-index = 1

Forward Citations = 11(Granted Patents)

Forward Citations (Not Self Cited) = 11(Sep 21, 2024)


Years Active: 2003-2008

where 'Filed Patents' based on already Granted Patents

2 patents (USPTO):

Title: The Innovative Mind of David J. Leffell: A Pioneer in Tumor Suppressor Research

Introduction: David J. Leffell, an accomplished inventor based in New Haven, CT, has made significant strides in the field of cancer research. With a focus on tumor suppressor genes, his contributions aim to understand and address the challenges of nevoid basal cell carcinoma syndrome and sporadic basal cell carcinomas. His innovative spirit is evidenced by his two patents, which are a testament to his dedication to cancer research.

Latest Patents: Leffell holds two notable patents that explore the mechanisms of tumor suppression. The first patent addresses the Basal Cell Carcinoma Tumor Suppressor Protein, which describes a tumor suppressor gene whose inactivation is a causal factor in nevoid basal cell carcinoma syndrome and various sporadic basal cell carcinomas. This invention identifies the NBCCS gene as a homologue of the patched (ptc) gene. The second patent also titled "Basal Cell Carcinoma Tumor Suppressor Gene," reinforces the importance of this gene in the same context, providing further insight into its role and implications.

Career Highlights: David J. Leffell works with the United States Department of Health and Human Services, where he continues to leverage his expertise in oncology and genetics. His research has not only contributed to the scientific community but also to potential therapeutic avenues for treating and understanding skin cancers.

Collaborations: Throughout his career, Leffell has collaborated with esteemed colleagues such as Michael C. Dean and Heidi Eve Hahn. These partnerships have fostered an environment of innovation and shared knowledge, propelling advancements in the understanding of tumor suppressor genes.

Conclusion: David J. Leffell stands as a pivotal figure in cancer research, particularly in the domain of tumor suppressor mechanisms. His patents underscore his commitment to unraveling the complexities of basal cell carcinoma, contributing valuable insights to both the scientific community and public health initiatives. As research continues to evolve, Leffell's work is likely to inspire future breakthroughs in cancer treatment and prevention.

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