David Guetig

Title: David Guetig: Innovator in Genomic DNA Methylation Detection

Introduction

David Guetig is a prominent inventor based in Berlin, Germany. He has made significant contributions to the field of genomic research, particularly in the detection of DNA methylation. His innovative methods have the potential to advance our understanding of genetic regulation and its implications in various biological processes.

Latest Patents

David Guetig holds a patent for a method titled "Method for determining the degree of methylation of defined cytosines in genomic DNA in the sequence context of 5'-CpG-3'." This method involves a unique approach to detect the degree of methylation of specific cytosines within genomic DNA samples. The process begins with the chemical treatment of genomic DNA, converting cytosine bases to uracil while leaving 5-methylcytosine bases unchanged. Subsequently, segments containing the specific cytosine are amplified, labeled, and analyzed to determine the extent of hybridization on two classes of oligonucleotides. The results provide insights into the methylation status of the cytosine in question.

Career Highlights

David Guetig is associated with Epigenomics AG, a company focused on developing innovative diagnostic solutions in the field of epigenetics. His work at the company has been instrumental in advancing research and applications related to DNA methylation.

Collaborations

Throughout his career, David has collaborated with notable colleagues, including Alexander Olek and Christian Piepenbrock. These collaborations have fostered a productive environment for innovation and research in genomic studies.

Conclusion

David Guetig's contributions to the field of genomic DNA methylation detection highlight his role as an influential inventor. His patented methods and collaborations continue to pave the way for advancements in genetic research and diagnostics.