David Frederick Mercer

Title: David Frederick Mercer: Innovator in Hepatology

Introduction

David Frederick Mercer is a prominent inventor based in Edmonton, Canada. He has made significant contributions to the field of hepatology, particularly in the development of animal models for studying human liver diseases. With a total of 6 patents to his name, Mercer is recognized for his innovative approaches to medical research.

Latest Patents

One of Mercer's latest patents is titled "Animal model having a chimeric human liver and susceptible to human hepatitis C virus infection." This invention features a non-human animal model that is susceptible to infection by human hepatotrophic pathogens, particularly the human hepatitis C virus (HCV). The model is based on an immunocompromised transgenic animal that possesses a human-mouse chimeric liver. The transgene allows for the expression of a urokinase-type plasminogen activator in the liver. This invention also includes methods for identifying candidate therapeutic agents, such as those with antiviral activity against HCV infection. Additionally, the animals developed through this invention are useful for assessing the toxicity of various agents and evaluating the activity of agents in reducing blood lipids.

Career Highlights

David Frederick Mercer is associated with Kmt Hepatech, Inc., where he continues to advance research in liver disease. His work has been instrumental in creating models that facilitate the understanding of hepatitis C and the development of potential treatments.

Collaborations

Mercer has collaborated with notable colleagues in his field, including Norman M Kneteman and D Lorne Tyrrell. These collaborations have further enhanced the impact of his research and innovations.

Conclusion

David Frederick Mercer is a key figure in the field of hepatology, with a focus on developing innovative animal models for studying liver diseases. His contributions are paving the way for advancements in the understanding and treatment of hepatitis C.