David A Battigelli

Title: Innovations by David A Battigelli

Introduction

David A Battigelli is an accomplished inventor based in Granger, IN (US). He holds 2 patents that showcase his expertise in microbiology and innovative methodologies. His work has significant implications for the detection and manipulation of bacteriophages, which are vital in various scientific and medical applications.

Latest Patents

One of his latest patents is a methodology for the detection, enumeration, propagation, and manipulation of bacteriophages. This method is designed to propagate, enumerate, and quantify bacteriophages in water samples or other aqueous environments. The methodology includes ingredients that stimulate the growth of specific bacterial species susceptible to infection by particular bacteriophages, while inhibiting or rendering inconsequential any interfering background organisms. Key features of the medium involve oxidation-reduction compounds that produce colored or fluorescent products, chromogenic and fluorogenic enzyme substrates, and temperature-independent gelling agents. A preferred combination includes 2,3,5-triphenyl tetrazolium chloride and 5-bromo-4-chloro-3-indolyl-B-D-galactoside, which, when used correctly, results in a dark red bacterial lawn with teal blue-green spots representing individual phage plaques, all visible under standard lighting conditions. This procedure can also be adapted for automatic counting systems under artificial illumination and is applicable to water samples and elution buffers that retain bacteriophages in suspension.

Another significant patent involves methods and apparatus to capture and release microbe particles using amino-functionalized silica substrates. This invention describes an apparatus designed to capture microbe particles, which includes a silica substrate coated with a positively charged material that features an aminopropyl functional group. This innovative approach enhances the efficiency of capturing microbe particles, contributing to advancements in microbiological research.

Career Highlights

David has worked with notable institutions such as the University of Notre Dame Du Lac and Scientific Methods, Inc. His contributions to these organizations have furthered research in microbiology and related fields.

Collaborations

Throughout his career, David has collaborated with esteemed colleagues, including Fu-Chih Hsu and Hsueh-Chia Chang. These partnerships have enriched his research and expanded the impact of his inventions.

Conclusion

David A Battigelli is a notable inventor whose work in bacteriophage detection and