Daniel J Wilkinson

Title: The Innovative Contributions of Daniel J Wilkinson

Introduction

Daniel J Wilkinson is a notable inventor based in Ypsilanti, MI (US). He has made significant strides in the field of medical research, particularly in the treatment of cystic fibrosis. His work has the potential to change the lives of many individuals affected by this genetic disease.

Latest Patents

Wilkinson holds a patent for a method of testing potential cystic fibrosis treating compounds. This invention addresses cystic fibrosis (CF), a lethal genetic disease caused by mutations in the gene coding for cystic fibrosis transmembrane conductance regulator (CFTR). His research revealed that not only wild type CFTR, but also several naturally-occurring CFTR mutants, expressed cAMP-activatable Cl currents. By treating these CFTR mutants with methylxanthine phosphodiesterase inhibitors, which increase cAMP levels, he found that Cl conductance could be activated to near wild type levels. This invention opens new avenues for treating cystic fibrosis through the administration of compounds that elevate cAMP levels.

Career Highlights

Wilkinson is affiliated with the University of Michigan, where he conducts his research. His work has garnered attention for its innovative approach to addressing a challenging medical condition. With 1 patent to his name, he continues to contribute to the scientific community.

Collaborations

Some of his notable coworkers include Francis S Collins and Mitchell L Drumm. Their collaboration has likely enhanced the impact of Wilkinson's research and broadened the scope of their collective work.

Conclusion

Daniel J Wilkinson's contributions to the field of cystic fibrosis research exemplify the importance of innovation in medicine. His patent offers hope for new treatment options for those affected by this genetic disorder.