Company Filing History:
Years Active: 2015-2023
Title: The Innovations of Daniel A. Nash
Introduction
Daniel A. Nash is a prominent inventor based in Madison, WI (US), known for his significant contributions to the field of nucleotide sequence assembly. With a total of 3 patents, Nash has developed innovative systems and methods that enhance the efficiency of genetic sequencing.
Latest Patents
Nash's latest patents include "Systems and methods for de novo assembly of nucleotide sequence reads using a modified string graph." This invention presents a method for automatically assembling unordered read sequences into larger nucleotide sequences. The process involves creating two identical sets of reads, dividing them into smaller sorted mer sequences, and comparing these sequences to identify overlapping segments. This overlap information is then used to construct a modified assembly string graph, which ultimately produces a sorted string graph layout file. This file is processed by a novel multiple sequence alignment system to determine an overall consensus sequence.
Another notable patent is "Systems and methods for identifying nucleotide sequence matches." This invention automatically identifies read sequences within larger nucleotide sequences by dividing the sequences into smaller mer sequences and sorting them. The pairwise comparison of these sorted sets reduces the volatile memory required and accelerates the identification of matches in nucleotide sequence databases.
Career Highlights
Nash is currently associated with Dnastar, Inc., where he continues to innovate in the field of genetic sequencing. His work has significantly impacted the efficiency and accuracy of nucleotide sequence assembly.
Collaborations
Throughout his career, Nash has collaborated with notable colleagues, including Frederick R. Blattner and Schuyler F. Baldwin. These collaborations have further advanced the research and development of genetic sequencing technologies.
Conclusion
Daniel A. Nash's contributions to the field of nucleotide sequencing through his innovative patents have made a lasting impact on genetic research. His work continues to pave the way for advancements in the understanding of genetic information.