Cécile Saint Cloment

Title: Cécile Saint Cloment: Innovating Neuronal Transport Analysis

Introduction

Cécile Saint Cloment is a pioneering inventor based in Paris, France, known for his innovative contributions to the field of neuroscience. With a focus on understanding and modulating neuronal transport, he has made significant strides in analyzing functional synaptic organization through his research.

Latest Patents

Saint Cloment holds a patent for his invention titled "In vivo modulation of neuronal transport." This innovative hybrid protein, referred to as GFP-TTC, comprises the non-toxic proteolytic C fragment of tetanus toxin fused to green fluorescent protein. His research demonstrates that when injected intramuscularly, GFP-TTC binds to tetanus neurotoxin receptors and rapidly clusters at the active neuromuscular junction. The study of membrane traffic facilitated by GFP-TTC reveals dynamic influences by neurotrophic factors, such as BDNF, NT-4, and GDNF, while noting that factors like NGF, NT-3, and CNTF did not yield similar effects. This groundbreaking work allows for novel methods of analyzing synaptic functioning and offers avenues for modulating neuronal transport.

Career Highlights

Throughout his career, Cécile has been affiliated with esteemed organizations like the Institut Pasteur and the Centre National de la Recherche Scientifique. His experience in these research institutions demonstrates his commitment to advancing scientific knowledge in neuronal transport and synaptic function.

Collaborations

Saint Cloment has collaborated with prominent colleagues in his field, including Sylvie Roux and Philippe Brulet. These partnerships have fostered valuable research initiatives that contribute to the understanding of neural networks and transport mechanisms.

Conclusion

Cécile Saint Cloment stands out as an influential inventor in the realm of neuroscience. His patent on the GFP-TTC hybrid protein opens new pathways for research in synaptic organization and neuronal transport modulation. With his collaborations and work at leading research institutions, Saint Cloment continues to make profound contributions to our understanding of the nervous system.