Denver, CO, United States of America

Curtis Coughlin, Ii


Average Co-Inventor Count = 3.0

ph-index = 1


Company Filing History:


Years Active: 2024

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1 patent (USPTO):Explore Patents

Title: Innovating Diagnosis: The Contributions of Curtis Coughlin, II

Introduction: Curtis Coughlin, II is an innovative inventor based in Denver, Colorado. With a deep focus on advancements in medical diagnostics, he holds a pivotal patent that has significant implications for diagnosing a rare neurological condition. His work primarily revolves around methods utilizing mass spectrometry for the quantification of specific compounds in biological samples.

Latest Patents: Coughlin's notable patent, titled "6-oxo-pipecolic acid quantitation by mass spectrometry," presents a method for determining the presence or amount of oxopiperidine in biological samples. This innovative approach can be used to efficiently and non-invasively diagnose pyridoxine-dependent epilepsy (PDE). This condition arises due to deficient a-aminoadipic-δ-semialdehyde (α-AASA) dehydrogenase activity, which is linked to mutations in the ALDH7A1 gene. The accumulation of Δ-P6C, P6CH, and 6-Oxo-PIP in biological samples can thus be accurately measured through his novel techniques.

Career Highlights: Curtis Coughlin, II has made significant strides in the field of medical research and diagnostics during his career at the University of Colorado. His innovative work has not only led to the development of crucial diagnostic methods but also has enhanced the understanding of biochemical pathways associated with neurological disorders. His singular patent stands as a testament to his dedication and contribution to advancing healthcare.

Collaborations: Throughout his career, Coughlin has collaborated with esteemed colleagues in the research community. One noteworthy collaboration is with Johan L. Van Hove, who shares a commitment to exploring and advancing the understanding of rare metabolic disorders. Their joint efforts exemplify the importance of teamwork in scientific innovation.

Conclusion: Curtis Coughlin, II's contributions to medical diagnostics underscore the importance of innovation in tackling complex health challenges. With his groundbreaking patent, he has paved the way for non-invasive diagnostic techniques that hold the potential to improve patient outcomes for individuals suffering from pyridoxine-dependent epilepsy. As he continues to collaborate with fellow researchers, his work remains vital in the ever-evolving landscape of medical science.

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