Company Filing History:
Years Active: 2020
Title: Conor Jacobs - Innovator in Protein Production Control
Introduction
Conor Jacobs is an accomplished inventor based in Stanford, California. He has made significant contributions to the field of protein production through his innovative research and development. His work focuses on engineered fusion proteins that offer new methods for controlling protein production.
Latest Patents
Conor Jacobs holds a patent for "Degron fusion constructs and methods for controlling protein production." This patent describes engineered fusion proteins that comprise a self-excising degron for controlling protein production. The invention includes fusion proteins that connect a degron to a protein of interest via a cleavable linker containing a hepatitis C virus (HCV) protease site. The degron can be removed by a czs-encoded HCV protease, allowing the protein of interest to be produced with minimal structural modification. Clinically available HCV protease inhibitors can block protease cleavage, ensuring that the degron is retained after inhibitor addition on subsequently synthesized protein copies. The degron, when attached, causes rapid degradation of the linked protein. This technology is particularly useful when precise control over protein production is required with minimal structural changes.
Career Highlights
Conor Jacobs is affiliated with Leland Stanford Junior University, where he conducts his research and development. His work has garnered attention for its potential applications in biotechnology and medicine. He has successfully developed methods that enhance the control of protein production, which is crucial for various scientific and clinical applications.
Collaborations
Conor Jacobs has collaborated with notable colleagues, including Michael Z Lin and Hokyung Chung. These collaborations have contributed to the advancement of his research and the development of innovative solutions in protein production.
Conclusion
Conor Jacobs is a pioneering inventor whose work in engineered fusion proteins is shaping the future of protein production control. His patent and research efforts are paving the way for advancements in biotechnology and medicine.