Rho, Italy

Claudio Pascali


 

Average Co-Inventor Count = 2.0

ph-index = 1


Company Filing History:


Years Active: 2015

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1 patent (USPTO):Explore Patents

Title: **Claudio Pascali: Innovator in Radioactive Tracer Development**

Introduction

Claudio Pascali, an inventive mind located in Rho, Italy, has made significant strides in the field of medical imaging through his innovative contributions. With a focus on the development of radioactive tracers, Pascali has successfully secured a patent that enhances the preparation of critical components used in tumor imaging.

Latest Patents

Pascali holds one notable patent that details a sophisticated procedure for the preparation of the radioactive tracer 3'-deoxy-3’-[F]fluorothymidine ([F]FLT). This innovative process consists of several key steps:

1. Preparation of anhydrous [F]F-fluoride.

2. Labelling of a precursor, such as 3-N-Boc-1-[5’-O-(4,4’-dimethoxytrityl)-3’-O-nitrophenylsulfonyl-2’-deoxy-β-D-lyxofuranosyl]thymidine.

3. Hydrolysis of the obtained mixture.

4. Purification of the mixture to finalize the radioactive tracer [F]FLT.

The purification step is particularly noteworthy, involving the use of a ventilated filter and various cartridges, such as cationic exchange and reversed phase types, to ensure the integrity of the final product.

Career Highlights

Claudio Pascali is associated with the Fondazione IRCCS Istituto Nazionale dei Tumori, an esteemed institution dedicated to cancer research and treatment. His work there reflects his commitment to advancing medical science and improving diagnostic techniques for cancer detection.

Collaborations

Pascali collaborates with Anna Bogni, a colleague at the Fondazione IRCCS Istituto Nazionale dei Tumori. Together, they contribute to the cutting-edge research that shakes the foundations of cancer diagnostics and therapeutics.

Conclusion

Claudio Pascali exemplifies the spirit of innovation in the medical field, specifically through the development of sophisticated radioactive tracers. His groundbreaking patent not only enhances tumor imaging but also represents the collaborative spirit that drives scientific advancements. As the field of medical imaging continues to evolve, Pascali’s contributions play a crucial role in shaping the future of cancer diagnosis and treatment.

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