Location History:
- Boston, MA (US) (1998)
- Cambridge, MA (US) (1998 - 2002)
Company Filing History:
Years Active: 1998-2002
Title: Innovations and Contributions of Chung-Ming Hsieh
Introduction
Chung-Ming Hsieh is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of biomedical research, particularly in the area of vascular biology. With a total of 5 patents to his name, Hsieh's work has the potential to impact medical treatments and diagnostics.
Latest Patents
Hsieh's latest patents include groundbreaking innovations such as striated-specific muscle cell polypeptides, specifically the Aortic-preferentially-expressed gene-1 (APEG-1) and striated muscle preferentially expressed (SPEG) polypeptide. These patents also cover DNA sequences that encode and control the transcription of the APEG-1/SPEG encoding gene. Additionally, he has developed methods for diagnosing vascular injury, conferring smooth muscle-cell specific expression, and inhibiting vascular smooth muscle cell proliferation by increasing the level of APEG-1 at the site of vascular injury. Another notable patent involves methods of modulating angiogenesis, specifically a method of inhibiting angiogenesis in a mammal by administering a compound that inhibits the binding of endothelial PAS domain protein-1 to the cis-acting transcription regulatory sequence in the promoter region of a gene encoding an angiogenic factor.
Career Highlights
Chung-Ming Hsieh is affiliated with Harvard College, where he conducts his research and develops his innovative ideas. His work has garnered attention in the scientific community, contributing to advancements in understanding vascular biology and potential therapeutic approaches.
Collaborations
Hsieh has collaborated with notable colleagues, including Mu-En Lee and Koji Maemura, to further enhance the impact of his research. These collaborations have allowed for a multidisciplinary approach to tackling complex biomedical challenges.
Conclusion
Chung-Ming Hsieh's contributions to the field of vascular biology through his patents and research at Harvard College highlight his role as an influential inventor. His innovative work continues to pave the way for advancements in medical science and potential treatments for vascular-related conditions.