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Title: Innovations of Chung-Hsiung Wang in Cell Line Development
Introduction
Chung-Hsiung Wang is a notable inventor based in Taipei, Taiwan. He has made significant contributions to the field of biotechnology, particularly in the development of novel cell lines derived from insect pupal tissues. With a total of 5 patents, his work has implications for pest control and the production of recombinant proteins.
Latest Patents
One of his latest patents involves the establishment of cell lines from pupal tissues, including NTU-MV, NTU-MV-1, and NTU-MV-2. These cell lines have been confirmed through karyotype analysis, Internal Transcribed Spacer (ITS) analysis, and isozyme analysis. They are distinct from other insect cell lines and are susceptible to multiple nucleopolyhedrovirus (MaviMNPV). This invention can be utilized for the in vitro multiplication of MaviMNPV to produce biopesticides for pest control. Additionally, these cell lines serve as hosts for expression vectors of baculovirus to produce recombinant proteins.
Another patent focuses on cell lines established from the pupal tissues of Swinhoe, including NTU-LY-1, NTU-LY-2, NTU-LY-3, and NTU-LY-4. These cell lines were confirmed to be newly established through random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) and isozyme analysis. They exhibit unique genotypes and characteristics compared to other insect cell lines and are susceptible to various insect-pathogenic microorganisms. This invention also has applications in the production of biopesticides and recombinant proteins.
Career Highlights
Chung-Hsiung Wang has worked with prestigious institutions such as the National Science Council and National Taiwan University. His research has significantly advanced the understanding and application of insect cell lines in biotechnology.
Collaborations
He has collaborated with notable colleagues, including Chu-Fang Lo and Guang-Hsiung Kou, contributing to the success of his research endeavors.
Conclusion
Chung-Hsiung Wang's innovative work in developing insect cell lines has opened new avenues for biopesticide production and recombinant protein expression. His contributions continue to impact the field of biotechnology positively.