Company Filing History:
Years Active: 2018-2025
Title: Christopher K Garcia: Innovator in Interleukin-2 Research
Introduction
Christopher K Garcia is a prominent inventor based in Menlo Park, California. He has made significant contributions to the field of biomedical research, particularly in the development of novel interleukin-2 (IL-2) muteins. With a total of four patents to his name, Garcia's work has the potential to impact various therapeutic applications.
Latest Patents
Garcia's latest patents focus on superagonists, partial agonists, and antagonists of interleukin-2. These patents describe novel human IL-2 muteins or variants that exhibit an increased binding capacity for the IL-2Rβ receptor while showing a decreased binding capacity for the IL-2Rγ receptor compared to wild-type IL-2. Such IL-2 muteins are particularly useful as partial agonists and antagonists in scenarios where the reduction or inhibition of IL-2 and/or IL-15 functions is beneficial. This includes applications in the treatment of graft versus host disease (GVHD) and adult T cell leukemia. Additionally, the patents cover nucleic acids encoding these IL-2 muteins, methods for their production, and pharmaceutical compositions that incorporate them.
Career Highlights
Throughout his career, Christopher K Garcia has worked with esteemed institutions such as Leland Stanford Junior University and the National Institutes of Health, a component of the US Department of Health & Human Services. His research has been pivotal in advancing our understanding of interleukin-2 and its therapeutic potential.
Collaborations
Garcia has collaborated with notable colleagues, including Suman Mitra and Warren Jaye Leonard. These partnerships have contributed to the innovative research and development of his patented technologies.
Conclusion
Christopher K Garcia stands out as a key figure in the field of interleukin-2 research, with his patents paving the way for new therapeutic strategies. His work exemplifies the intersection of innovation and healthcare, highlighting the importance of continued research in this vital area.
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