Location History:
- Kew, GB (1982)
- Richmond, GB (1987)
Company Filing History:
Years Active: 1982-1987
Title: Christopher J Bruton: Innovator in Enzyme Production
Introduction
Christopher J Bruton is a notable inventor based in Kew, GB. He has made significant contributions to the field of enzyme production, holding 2 patents that showcase his innovative work. His research focuses on the development of chimeric plasmids and the production of glycerol dehydrogenase enzymes with exceptional thermal stability.
Latest Patents
Bruton's latest patents include advancements in chimeric plasmids and methods for producing glycerol dehydrogenase enzymes. These enzymes are derived from novel strains of Bacillus stearothermophilus, which are cultured under specific conditions to enhance their stability and activity. The procedures outlined in his patents detail the growth of these strains in conventional culture media, particularly with glycerol or its analogues, at temperatures ranging from 40 to 65 degrees Celsius and a pH of 5 to 8. The resulting enzymes exhibit a molecular weight of approximately 240,000, composed of four similar sub-units, and demonstrate a specific activity of greater than 5 Units per mg of protein at 30 degrees Celsius. These enzymes can be utilized for serum triglyceride assays, preferably using the nicotinamide adenine dinucleotide spectrophotometric method.
Career Highlights
Throughout his career, Christopher J Bruton has worked with several reputable organizations, including the Public Health Laboratory Service and the Center for Applied Microbiology. His experience in these institutions has contributed to his expertise in microbiology and enzyme production.
Collaborations
Bruton has collaborated with notable colleagues such as Anthony Atkinson and Michael J Comer, further enhancing his research and development efforts in the field of enzyme technology.
Conclusion
Christopher J Bruton is a distinguished inventor whose work in enzyme production has led to significant advancements in the field. His innovative patents and collaborations reflect his commitment to scientific progress and the development of practical applications in microbiology.