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Title: Christine Beeton: Innovator in Potassium Channel Inhibition
Introduction
Christine Beeton is a prominent inventor based in Irvine, CA, known for her significant contributions to the field of biochemistry and pharmacology. She holds 4 patents that focus on the innovative use of ShK toxins in the selective inhibition of Kv1.3 potassium channels. Her work has the potential to impact the treatment of various diseases and disorders.
Latest Patents
Among her latest patents, Christine has developed analogs of ShK toxin and methods for their use in selective inhibition of Kv1.3 potassium channels. These ShK analogs generally comprise ShK toxin attached to a chemical entity that possesses an anionic charge. The analogs can be administered to both human and non-human animal subjects to inhibit potassium channels or to treat specific diseases. In some embodiments, the chemical entity may include an amino acid residue, enhancing the specificity of the inhibition. Additionally, some analogs may be tagged with a fluorophore, allowing for their use in flow cytometry and in conjunction with class II tetramers to detect autoreactive cells.
Career Highlights
Christine has worked with esteemed organizations such as the University of California and Bachem Biosciences, Inc. Her research has been pivotal in advancing the understanding of potassium channels and their role in various physiological processes.
Collaborations
Christine has collaborated with notable scientists in her field, including George Chandy and Michael William Pennington. These collaborations have further enriched her research and contributed to her innovative work.
Conclusion
Christine Beeton's contributions to the field of potassium channel inhibition through her innovative patents highlight her role as a leading inventor. Her work continues to pave the way for advancements in medical treatments and therapies.