Company Filing History:
Years Active: 1996-2007
Title: Innovations of Christian Huber in Nucleic Acid Separation
Introduction
Christian Huber is an accomplished inventor based in Rum, Austria. He has made significant contributions to the field of chromatography, particularly in the separation of polynucleotides. With a total of two patents to his name, Huber's work has advanced the methodologies used in nucleic acid analysis.
Latest Patents
Huber's latest patents include a method and apparatus for separating polynucleotides using monolithic capillary columns. This innovative approach utilizes methods and devices based on capillary monolithic columns, specifically those made from underivatized poly(styrene-divinylbenzene) monoliths. The technology allows for the efficient separation of a mixture of polynucleotides through ion pair-reverse phase-high performance chromatography (IP-RP-HPLC). Key features of this invention include the monolith's high theoretical plate count, the absence of retaining frits, and the ability to incorporate the monolith into miniaturized chromatography systems that can be coupled with mass spectrometers for on-line analysis.
Another notable patent involves nucleic acid separation on alkylated nonporous polymer beads. These beads, with an average diameter of 1-100 microns, are designed for effective chromatographic separation of nucleic acids when alkylated with chains of at least three carbon atoms. This method enhances the efficiency of nucleic acid separation using ion-pair reverse phase chromatography.
Career Highlights
Throughout his career, Christian Huber has worked with notable companies such as Sarasep, Inc. and Transgenomic, Inc. His expertise in chromatography and nucleic acid separation has positioned him as a key figure in the field.
Collaborations
Huber's collaborations include working alongside esteemed colleagues such as Gunther Bonn and Peter Oefner. Their combined efforts have contributed to advancements in the methodologies used in nucleic acid analysis.
Conclusion
Christian Huber's innovative patents and career achievements have significantly impacted the field of nucleic acid separation. His work continues to influence advancements in chromatography and related technologies.
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