Company Filing History:
Years Active: 2001-2002
Title: Innovations of Chonghua Zhou
Introduction
Chonghua Zhou is an accomplished inventor based in Ellicott City, MD (US). He holds 2 patents that showcase his expertise in the field of biosensor technology. His work focuses on enhancing the detection of pathogens, particularly Salmonella, through innovative fiber-optic systems.
Latest Patents
Zhou's latest patents include an acoustic standing-wave enhancement of a fiber-optic Salmonella biosensor. This fluorescent fiber-optic biosensor system utilizes ultrasonic concentration of particles and cells for the detection of Salmonella typhimurium. The biosensor test chamber functions as an ultrasonic standing-wave cell, allowing microspheres or cells to be concentrated in parallel layers or in a column along the axis of the cell. A fiber probe along the axis delivers laser excitation to fluorescent-labeled antibodies of Salmonella and collects the fluorescent signal. The Salmonella-antibody complexes are acoustically moved to the axis of the cell, which increases the fluorescent signal. Alternatively, the Salmonella-labeled antibody complexes can attach to unlabeled antibodies immobilized on the surface of polystyrene microspheres. This entire structure can be manipulated acoustically, and the increase in the fluorescent signal, which can be an order of magnitude, indicates the presence of Salmonella.
Career Highlights
Throughout his career, Zhou has worked with notable organizations, including the Board of Governors for Higher Education, State of Rhode Island and Providence Plantations. His contributions to the field of biosensors have been significant, particularly in the development of systems that enhance pathogen detection.
Collaborations
Zhou has collaborated with professionals such as Stephen V Letcher and A Garth Rand, further enriching his work and expanding the impact of his innovations.
Conclusion
Chonghua Zhou's contributions to biosensor technology demonstrate his commitment to advancing the detection of pathogens. His innovative approaches have the potential to significantly improve public health safety.