Company Filing History:
Years Active: 2008-2023
Title: The Innovative Contributions of Chihaya Imai
Introduction
Chihaya Imai is a notable inventor based in Niigata, Japan, recognized for his groundbreaking work in the field of immunology. With a remarkable portfolio of seven patents, Imai's contributions have significantly advanced the understanding and treatment of immune cell activation.
Latest Patents
Among his latest innovations, Imai has developed advanced methods for expanding immune cells. One of his patents involves a chimeric receptor that effectively signals both a primary and a co-stimulatory pathway. This innovation allows for the activation of the co-stimulatory pathway, even in the absence of natural ligand binding. The receptor’s cytoplasmic domain encompasses a portion of the 4-1BB signaling domain, enhancing its functionality. Further embodiments of this invention include polynucleotides encoding the receptor, alongside vectors and host cells that express chimeric receptors, particularly focusing on T cells and natural killer (NK) cells, expanding their application methods.
Another significant patent by Imai revolves around chimeric receptors that contain the 4-1BB stimulatory signaling domain. This invention similarly allows the signaling of both primary and co-stimulatory pathways, contributing towards enhanced immune responses in therapeutic settings.
Career Highlights
Chihaya Imai is affiliated with St. Jude Children's Research Hospital, where he continues to innovate and research methods to harness the potential of immune cells in combating diseases. His work not only reflects his expertise in the field but also underlines the importance of novel therapeutic strategies in immunology.
Collaborations
Imai frequently collaborates with fellow researchers, including Dario Campana, to explore new frontiers in immunotherapy. These collaborative efforts amplify the research impact and foster an environment of innovation and discovery.
Conclusion
Chihaya Imai's inventive spirit and scientific acumen position him as a key figure in advancing immunological therapies. His patents demonstrate a commitment to harnessing immune cell capabilities, paving the way for future innovations that can transform patient care in various medical disciplines.