Chih-hu Ho

Title: Chih-hu Ho: Innovator in Metal-Chelating Surfactants

Introduction

Chih-hu Ho is a notable inventor based in Sandy, Utah, recognized for his contributions to the field of surfactants. His innovative work focuses on the development of a modified surfactant that has significant applications in protein immobilization.

Latest Patents

Chih-hu Ho holds a patent for a "Metal-chelating surfactant," which describes a modified surfactant of the PLURONIC.TM.-type compound and a method for its manufacture. This surfactant compound features at least one PEO block attached at one end to at least one PPO block. Notably, at least one of the PEO blocks has an organic metal-chelating end group attached to its second end, while the remaining PEO blocks possess an unmodified hydroxyl group. The metal-chelating group is charged with a metal ion, allowing for complex formation with proteins that have metal-affinity tags, such as histidine tags. This innovative surfactant can be adsorbed onto hydrophobic surfaces, charged with metal ions, and complexed with proteins, making it suitable for applications requiring specific protein activity on surfaces.

Career Highlights

Chih-hu Ho is affiliated with the University of Utah Research Foundation, where he continues to advance his research in surfactants and their applications. His work has led to significant advancements in the field, particularly in the area of protein immobilization.

Collaborations

Chih-hu Ho has collaborated with notable colleagues, including Russell John Stewart and Karin D Caldwell, contributing to the advancement of research in surfactants and their applications.

Conclusion

Chih-hu Ho's innovative work in developing metal-chelating surfactants represents a significant advancement in the field of biochemistry. His contributions have the potential to enhance various applications in protein immobilization and surface activity.