Title: Chasper Puorger - Innovator in Bioconjugation
Introduction
Chasper Puorger is an inventor based in Basel, Switzerland. He is currently associated with NBE-Therapeutics AG, where he focuses on innovative methods in bioconjugation. Although he has not yet been granted any patents, his work is significant in the field of biotechnology.
Latest Patent Applications
Chasper Puorger's notable patent application is titled "Sortase F and Its Use in Methods for Conjugation." This invention relates to a method for producing a conjugate of two substrates. The method involves providing two substrates, each selected from groups consisting of small molecules and proteins. The enzymatic conjugation of the two substrates is achieved using a sortase F enzyme or a catalytic domain thereof. One substrate contains a sortase F recognition motif, while the other substrate includes at least one motif selected from a Glymotif, an Alamotif, or a mixture of Ala and Gly residues. The reaction occurs in an aqueous medium with a salt concentration ranging from about 0.01 to 3 M, resulting in a conjugated product of the two substrates.
Conclusion
Chasper Puorger is an emerging inventor in the field of bioconjugation, contributing valuable research and applications that may lead to significant advancements in biotechnology. His work, particularly in the area of sortase F enzyme applications, showcases his innovative approach to scientific challenges.